Epilepsy: A Queen Square Textbook brings together the science and clinical study of adult epilepsy. Edited by John S. Duncan and Ley Sander, this first edition covers classification, causes, neurophysiology, imaging, medication, surgical evaluation, and psychosocial concerns for neurologists, epilepsy trainees, and researchers studying seizure disorders.
Inside this title
Adult epilepsy classification, epidemiology, genetic causes, and acquired causes
Current listed price $40.99Regular price $105.00Digital ebook
The volume moves from definitions and epidemiology into the mechanisms and causes of epilepsy. Genetic and acquired factors, neurophysiology, and seizure classification establish a basis for chapters on assessment. Imaging discussions consider structural and functional methods in relation to localization and the evaluation of patients for surgery.
Treatment sections address pharmacological principles, medication effects and interactions, drug-resistant epilepsy, and surgical approaches. Cognitive and psychiatric comorbidities, social stigma, and quality of life broaden the account beyond seizures themselves. Emerging treatments and clinical research also receive attention. The first edition is intended for clinicians and researchers across neurology, neurophysiology, neuropsychology, imaging, and related areas of adult epilepsy care.
Study guide included
Inside Epilepsy: A Queen Square Textbook, 1st Edition.
A clinical reference on adult epilepsy that joins basic science with bedside practice. Edited by Duncan and Sander, it moves from classification and causes through neurophysiology and imaging to medication, surgical evaluation, and the cognitive, psychiatric, and social dimensions of living with seizures.
The volume establishes foundations in definitions, epidemiology, and the genetic and acquired causes of epilepsy, then explains neurophysiology and seizure classification as the basis for assessment. Structural and functional imaging are discussed in relation to localization and surgical workup. Treatment coverage includes pharmacological principles, drug effects and interactions, drug-resistant epilepsy, and operative approaches. Chapters on cognitive and psychiatric comorbidity, stigma, and quality of life widen the frame beyond seizure control, and emerging treatments and clinical research are also addressed. The edition is aimed at adult epilepsy practice and research.
Classification and Epidemiology of Epilepsy
The text begins by defining seizure types and epilepsy syndromes and by describing how often they occur across populations. Classification is presented as a working tool that guides assessment and treatment rather than a fixed label. Readers see how epidemiologic patterns inform questions about cause, prognosis, and service planning.
Use classification to guide assessment
Read incidence and prevalence patterns
Connect epidemiology to prognosis and planning
Topics 1–2
Genetic and Acquired Causes
Causes are treated as overlapping rather than exclusive. Genetic contributions, structural abnormalities, injury, infection, and other acquired factors are examined for how they produce a seizure tendency. The discussion shows why identifying a cause changes both counseling and the choice of further investigation for an individual patient.
Weigh genetic contributions to epilepsy
Identify acquired and structural causes
Link cause to counseling and workup
Topic 3
Neurophysiology and Seizure Mechanisms
The book explains how normal neuronal excitability becomes abnormal synchronization. Readers encounter the physiological ideas that underlie seizure generation and spread, providing a basis for interpreting EEG findings and clinical semiology. The emphasis is on mechanisms that make assessment and treatment reasoning intelligible to clinicians.
Trace abnormal neuronal synchronization
Connect physiology to EEG interpretation
Relate mechanisms to seizure semiology
Topic 4
Imaging and Surgical Localization
Structural and functional imaging are presented as complementary ways to locate a seizure focus. The text relates imaging findings to localization and to the evaluation of candidates for surgery. Readers see how imaging contributes to a decision that depends on concordance with other clinical evidence.
Compare structural and functional imaging
Relate findings to seizure localization
Assess concordance before surgical workup
Topic 5
Pharmacology and Drug-Resistant Epilepsy
Treatment chapters cover pharmacological principles, drug effects, and interactions, then address the problem of seizures that persist despite medication. Readers examine how drug selection and resistance are reasoned about, why some patients require evaluation for surgery or other options, and how risk and benefit are weighed over time.
Apply pharmacological principles to drug choice
Watch for effects and interactions
Recognize and evaluate drug resistance
Topics 6–7
Comorbidities, Stigma, and Quality of Life
The text widens the clinical picture to cognitive and psychiatric comorbidity, social stigma, and everyday quality of life. These concerns are treated as part of epilepsy care rather than distractions from seizure control. Readers consider how psychosocial context shapes outcomes, clinical priorities, and the way services are organized.
Screen for cognitive and psychiatric comorbidity
Address stigma in clinical care
Include quality of life in outcomes
Topic 8
Topic map
Definitions and classificationTopic 1
Epidemiology and population patternsTopic 2
Genetic and acquired causesTopic 3
Neurophysiology and mechanismsTopic 4
Imaging and localizationTopic 5
Medication principles and interactionsTopic 6
Drug-resistant epilepsy and surgeryTopic 7
Comorbidity, stigma, quality of lifeTopic 8
Key takeaways
Use classification and epidemiology as working tools that shape assessment, prognosis, and service planning.
Combine imaging with clinical evidence, and weigh concordance before pursuing surgical evaluation.
Include cognitive, psychiatric, and social outcomes when judging the value of epilepsy treatment.
Neurologists, epilepsy fellows and trainees, neurophysiologists, imaging and neuropsychology specialists, and researchers focused on adult seizure disorders and their long-term clinical management across care settings.
Topics covered
adult epilepsy
seizure classification
epilepsy imaging
drug-resistant epilepsy
epilepsy surgery
epilepsy neurophysiology
quality of life
Questions about this ebook.
Edition, audience, and study-guide details at a glance.
What is Epilepsy: A Queen Square Textbook, 1st Edition about?
Epilepsy: A Queen Square Textbook brings together the science and clinical study of adult epilepsy. Edited by John S. Duncan and Ley Sander, this first edition covers classification, causes, neurophysiology, imaging, medication, surgical evaluation, and psychosocial concerns for neurologists, epilepsy trainees, and researchers studying seizure disorders.
Which edition of Epilepsy: A Queen Square Textbook, 1st Edition is this?
This listing is for the 1st edition. Check the title, ISBN, and book details above before ordering, especially if your course or reading list names a specific edition.
Who is Epilepsy: A Queen Square Textbook, 1st Edition for?
Neurologists, epilepsy fellows and trainees, neurophysiologists, imaging and neuropsychology specialists, and researchers focused on adult seizure disorders and their long-term clinical management across care settings.
Does this page include a study guide?
Yes. This page includes an original study guide with six thematic sections, key takeaways, and a topic map for structured reading.
